Hosts Barcelona have won four of their last five matches in the Champions League, scoring seven goals last time out at home against Newcastle.
Five of the Catalonians' last eight outings in Europe's elite club competition have produced over 3.5 goals, and three of those high-scoring games have been played at the Spotify Camp Nou.
Visitors Atletico Madrid have seen over 3.5 goals in nine of their 12 Champions League matches this season, including each of their last four fixtures.
Diego Simeone's side have only managed to win two of their last six European games, but have only failed to score once in European competition this season.
Barcelona have won five of the last six encounters between these two clubs across all competitions, which includes their La Liga clash in Madrid at the weekend.
At least four goals have been scored in four of the last seven head-to-heads between these two great rivals, with Barcelona scoring at least three goals in four of those matches.
We're backing the home side to come out on top on Wednesday night, but expect Atletico Madrid to find the back of the net at least once as they have done in all but one of their Champions League matches on the run to the quarter-finals.
Barcelona 3-1 Atletico Madrid
