Paddy Power have a range of #WhatOddsPaddy Bet Builders for this match, and we've picked out two eye catchers:
England to win, Henry Arundell to score a try, George Ford to score 12+ points, any Scotland player yellow carded - 17/2
If you're an England fan, this is a great one for you. Arundell scored a hatrick versus Wales, and Ford contributed 11 points through 4 conversions and a penalty.
Expect more kickable penalties with Scotland's defensive likely to hold up England's attack at the try line better than Wales managed. Extensive try line pressure always leads to yellow cards too.
1+ yellow card, 1+ red card & 1+ successful drop goal in the match - 25/1
England's opener vs Wales saw 4 players sent to the sin bin, while Scotland also had a player yellow carded. In a high intensity match like this, a red is always a possibility, especially with the much stricter high tackle laws.
As for drop goals - George Ford has scored 10 across his 105 caps, and it's a highly effective tactic he uses to great effect at club level too.