Thomas Tuchel's side is expected to line up strongly against Wales on Thursday, given their next game against Latvia is likely to be a formality as they look to secure their place in next year's FIFA World Cup.
England's record in qualifying has seen the Three Lions pick up 15 points from five matches. Still, first they face a test from a Wales side who could use this eagerly anticipated clash between two rivals as a springboard for their qualifying campaign.
Thomas Tuchel has caused some headlines with his squad selection process, omitting the likes of Adam Wharton (Crystal Palace) and, more notably, Jack Grealish, whose performances for Everton earned him August Player of the Month for the Premier League.
As mentioned, England has maintained a perfect record in qualifying. However, goals haven't been flowing freely for the home side, with the result against Andorra (0-1) in particular causing concern among the England faithful.
As for Wales, they suffered their second defeat in three matches, falling 1-0 to Canada. The Dragons have picked up 10 points in their qualifying group, although the 4-3 defeat against Belgium has given the likes of North Macedonia and the Red Devils momentum in that group. Tuchel's side have the advantage in this fixture, having won the last seven meetings between the two sides, with six clean sheets in those seven
That being said, we can see a routine 2-0 victory at Wembley for the Three Lions.
England 2-0 Wales
