Southampton vs Arsenal 45/1 Bet Builder Tip 04/04/2026

Arsenal are still working towards a historic treble this season as they take on Southampton in the FA Cup quarterfinal this weekend.

After a tough start to the season, Southampton have improved under manager Tonda Eckert as they campaign has progressed, and they now look on course to seal a play-off spot.

The Saints have a decent recent record in this competition, reaching the semi-finals in 2020-21 and the quarterfinals in 2021-22, and while the odds are stacked against them here, they'll feel confident of giving a good account of themselves.

Arsenal, meanwhile, are top of the Premier League and are hoping to take a step towards what they hope will be a treble come May.

The team seems to be struggling with injuries, with many big name players forced to withdraw from international duty, but there is plenty enough talent in the squad to get the job done.

Based on that, we've picked out a 45/1 mega bet builder tip for Saturday's game. Scroll down to see our selections!

Our selections have been carefully selected by our expert betting team:

• Arsenal To Win
• Gabriel Jesus To Score Anytime
• Taylor Harwood-Bellis To Be Carded
• Shea Charles To Be Carded
• Gabriel Martinelli To Be Carded

Arsenal To Win

Arsenal are the heavy favourites for this game, as they enter the tie top of the Premier League, with Southampton sitting 7th in the Championship. The Gunners have also lost only one of their last 15 games, which was at the hands of Manchester City.

Gabriel Jesus To Score Anytime

Brazilian Gabriel Jesus is set to start for Arsenal, and while the striker has been short of meaningful minutes this season, his goals per 90 rate is very impressive, currently at 0.57.

Taylor Harwood-Bellis To Be Carded

Centre-back Taylor Harwood-Bellis Southampton's second most-carded player this season, with ten bookings to his name. The defender has also committed 29 fouls, putting him in the top five in the squad for that metric.

Shea Charles To Be Carded

Midfielder Shea Charles has averaged 0.29 cards per 90 this season, giving him one of the highest bookings rates of any Saints player. Having committed 33 fouls, he's also one of the team's most prolific foul committers.

Gabriel Martinelli To Have 1+ Shots On Target

Fresh off the back of a goal for Brazil in midweek, Gabriel Martinelli will be in good shape ahead of this one. The Arsenal forward has averaged over one shot on target per 90 this season.