Czech Republic faces Switzerland in Prague as one will look to get a head start in the likely battle to avoid relegation in League A Group 2.
The last edition of the Nations League proved successful for the Euro 2020 quarter-finalists, as the Central European nation gained promotion from League B. In their last eight games, however, the Czech Republic, featuring the likes of Tomas Soucek and Patrick Schick, has only won games against Belarus and Estonia.
Switzerland continues to prove time and time again not to be underestimated. The team who knocked out World Champions France at last year's Euros claimed another scalp in World Cup qualifying, finishing above Italy and ultimately costing the European Champions a place in Qatar.
The Swiss have only lost to England in their last 11 games, so an away win is likely in Prague.