The first tip on this list sees Leicester, Newcastle, Southampton and Wolves all need to score two or more goals.
Leicester and Southampton face League One sides in MK Dons and Lincoln City, while Wolves hosts bottom of the Football League Gillingham at Molineux. On top of this, Newcastle goes head to head with Bournemouth at St James’ Park and will be desperate to replicate the early season form that sees them sit third in the Premier League standings.
On Tuesday night, MK Dons and Leicester City go head to head at Stadium MK, with the Foxes looking to return to action with a victory over 22nd in League One.
James Maddison is Leicester City’s top scorer so far this campaign and will be fresh, having not played a single minute at the World Cup with England. The 26-year-old will be eager to impress and is priced at 9/2 to score the first goal of the game.
An all-Premier League tie takes place between Newcastle United and AFC Bournemouth on Tuesday, with Eddie Howe’s men looking to reach the quarter-finals.
Before the start of the World Cup, Paraguayan midfielder Miguel Almiron was in the best form of his career, scoring eight goals and creating one assist in 15 Premier League matches.
The 28-year-old former Atlanta United man has managed two goals from outside the penalty area this campaign.
Nathan Jones will take charge of his second game as Southampton manager on Tuesday when the Saints host Lincoln City at Saint Mary’s.
The Welshman will be eager to get a win here, having seen his side lose 3-1 to Liverpool at Anfield in his debut match. Notably, Che Adams scored an equaliser in that game and the Scotland international is the player that we have tipped to score first.
Leicester-born striker, Adams, is the Saints' top scorer so far this season, with six goals in 15 matches, including two goals in the last round of the Carabao Cup in a 3-0 win away at Cambridge United.
Wolves will be looking to start life under Julen Lopetegui in a good fashion when they face League Two outfit, Gillingham, at Molineux.
Lopetegui will likely start a strong squad as he looks to implement his tactics from the off. The Spaniard will also be keen to avoid the same fate as Brentford did in the last round when they were beaten by the Gills 6-5 on penalties after a 1-1 draw despite having 16 shots to their opponent’s one.
Adama Traore has scored twice this season, including in Wolves’ second-round win over Preston North End at Molineux. Meanwhile, summer signing Goncalo Guedes will be determined to find his feet, having only scored one goal in 14 matches. Prior to joining Wolves, the 26-year-old Portuguese forward had managed 19 goal contributions in 42 appearances for Valencia.
Manchester City are in dire need of a result as they welcome Feyenoord to Manchester in the Champions League this week. Pep Guardiola's side find themselves in an unprecented posit...
