Uruguay have been really struggling as of late and are in danger of not qualifying for the World Cup, with their last game against Paraguay snapping a four-game losing streak.
Venezuela are also struggling and are currently bottom of the qualification standings, but a win in their last game out against Bolivia, who previously beat Uruguay 3-0, could give them more confidence coming into this fixture.
Their last meeting in June of last year ended in a 0-0 draw in a very even contest where neither side imposed themselves on the game, and that could similarly play out in this fixture.