United generally have a good record against Brentford at Old Trafford, winning all of the last three head-to-head games at Old Trafford.
Brentford's away form in the league has also been poor, with the Bees losing four of their last five league games on the road.
This will likely be a very close and competitive affair, but we're backing Ten Hag's side to edge it. Man Utd 2-1 Brentford.